KMID : 1129720060230020105
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Korean Journal of Acupuncture 2006 Volume.23 No. 2 p.105 ~ p.111
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Electroacupuncture suppresses epileptic EEG in experimental induced epileptic rats
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Kim Yun-Jin
Kim Jae-Hyo Ma Cheng Shen Mei-Hong Li Zhong-Ren Sohn In-Chul
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Abstract
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Objectives: We investigated the effect of electroacupuncture on epileptic rat model and its underlying mechanisms on suppression of the epilepsy.
Methods: It was used pentylenetetrazol induced epileptic rat model and square wave electrical stimulations (5 mA, 5, 40 or 80 Hz frequency) was applied to acupoints on ¡¯Dazhui¡¯ and ¡¯Taichong¡¯ for 30min.
Results: Electroacupuncture suppressed spikes and slow waves of EEG due to the epileptic condition. Out of electroacupuncture, a high frequency of 80Hz had a better effect for suppress epileptic EEG wave.
Conclusions: Electroacupuncture can markedly reduce the excitability of cerebral cortex and strengthen the inhibitory process, checking epilepsy wave. Some intrathalamic nuclei have a promoting or inhibiting effect on epileptic EEG wave. This experimental study we are proposed to Electro-acupuncture can suppression epileptic rat model and it¡¯s scientific mechanisms.
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KEYWORD
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electroacupuncture, epilepsy, electroencephalogram
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